Journal of Andrology
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Published-Ahead-of-Print April 23, 2009, DOI:10.2164/jandrol.108.007344

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A Novel Treatment Modality in Patients with Premature Ejeculation Resistant to Conventional Methods: The Neuromodulation of Dorsal Penile Nerves by Pulsed Radiofrequency

Seref Basal *, Serdar Goktas , Atilla Ergin , Ibrahim Yildirim , Abdulkadir Atim , Lutfi Tahmaz , and Murat Dayanc

* To whom correspondence should be addressed. E-mail: serefbasal{at}gmail.com.

Premature ejaculation (PE) is the most common sexual problem experienced by men, and affecting 20%–30% of them. Pulsed radiofrequency (PRF) neuromodulation has been shown to be an effective treatment for a wide range of pain conditions. We used PRF to treat PE by desensitizing dorsal penile nerves in patients resistant to conventional treatments. Fifteen patients with a lifelong history of PE were defined as an intravaginal ejaculatory latency time (IELT) of <1 min that occurred in more than 90% of intercourses and resistant to conventional treatments were enrolled in this study. Patients with erectile dysfunction were excluded. The mean age of the patients was 39 ± 9 years. Before and 3 weeks after the treatment, IELT and sexual satisfaction scores (SSS) (for patients and their partners) were obtained. The mean IELT before and 3 weeks after procedure were 18.5 ± 17.9 and 139.9 ± 55.1 seconds, respectively. Any side effects did not occur. Mean SSS of patients before and after treatment were 1.3 ± 0.3 and 4.6 ± 0.5 and mean SSS of partners before and after treatment were 1.3 ± 0.4 and 4.4 ± 0.5 respectively. In all cases, IELT and SSS were significantly increased (p<0.05). None of the patients and their wives defined any treatment failure during the follow-up period. The mean follow-up time was 8.3 ± 1.9 months. It is early to conclude that this new treatment modality might be used widely for the treatment of PE, however being an innovative modality, placebo controlled studies (e.g. sham procedure), with larger number of patients, including assessment of penil sensitivity (e.g. biothesiometry) are needed.


Key words: Premature ejaculation • Pulsed radiofrequency




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S. Basal, A. Ergin, I. Yildirim, S. Goktas, A. Atim, A. Sizlan, H. C. Irkilata, E. Kurt, and M. Dayanc
A Novel Treatment of Chronic Orchialgia
J Androl, January 1, 2012; 33(1): 22 - 26.
[Abstract] [Full Text] [PDF]


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