Journal of Andrology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Published-Ahead-of-Print February 19, 2009, DOI:10.2164/jandrol.108.007195

This Article
Right arrow Author Manuscript (PDF)
Right arrow All Versions of this Article:
30/5/520    most recent
Author Manuscript (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Elbendary, M. A.
Right arrow Articles by Salem, K. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Elbendary, M. A.
Right arrow Articles by Salem, K. A.

Analysis of Risk Factors for Organic Erectile Dysfunction in Egyptian Patients under the Age of 40 Years

Mohamed A. Elbendary , Osama M. El-Gamal *, and Khaled A. Salem

* To whom correspondence should be addressed. E-mail: elgamalmd{at}yahoo.co.uk.

Many of the risk factors have been implicated in the pathogenesis of the erectile dysfunction (ED) but it is not clearly evident which of these factors are more relevant among the young population. The aim of this project was to find the most significant risk factors for this disease in young patients. We included 434 patients with organic ED below the age of 40 years and 272 age-matched controls. All participants were subjected to complete history taking (including the International Index of Erectile Function-5 (IIEF-5)), physical examination and some laboratory investigations. The univariate analysis was then applied to study the significance of the following factors in the predisposition of the ED: smoking, use of recreational drugs, obesity, dyslipidemia, diabetes mellitus (DM), hypertension, coronary heart disease (CHD) and chronic pelvic pain syndrome (CPPS). This analysis showed that smoking, use of recreational drugs, dyslipidemia, hypertension and obesity were the significant ones (p<0.05 for each factor). When these significant factors were studied in the multivariate model, the only factors that sustained the statistical significance were smoking (p < 0.05, OR=1.78, 95%CI=1.16-2.72) and use of recreational drugs (p < 0.05, OR=3.18, 95%CI=1.15-8.82). In addition, a negative correlation was detected between the smoking index of the impotent patients and their IIEF-5 score (r2=0.67, p<0.05). In conclusion, smoking and the use of recreational drugs are the most significant risk factors for organic ED in patients under 40 years.


Key words: Erectile Dysfunction • risk factors • young patients






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Copyright © 2009 by The American Society of Andrology.