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* To whom correspondence should be addressed. E-mail: jshuang{at}vghtpe.gov.tw.
The aim of this study was to evaluate the accuracy of different methods, including Seager's orchidometer (SO) and ultrasonography (US), for assessing testicular volume of smaller testes. Moreover, the equations used for the calculations, i.e. Hansen's formula (L x W2 x 0.52, equation A), the prolate ellipsoid formula (L x W x H x 0.52, equation B), and Lambert's equation (L x W x H x 0.71, equation C), were also examined and compared with the gold standard testicular volume obtained by water displacement (Archimedes principle). In this study, 30 testes from 15 men, mean age 75.3 (± 8.3), were included. They all had advanced prostate cancer and were admitted for orchiectomy. Before the procedure, all the testes were assessed using SO and US. The dimensions were then input into each equation to obtain the volume estimates. The testicular volume by water displacement was 8.1 ± 3.5 mL. Correlation coefficients (R2) of the two different methods (SO, US) to the gold standard were 0.70 and 0.85, respectively. The calculated testicular volumes were 9.2 ± 3.9 mL (measured by SO, equation A), 11.9 ± 5.2 mL (measured by SO, equation C), 7.3 ± 4.2 mL (measured by US, equation A), 6.5 ± 3.3 mL (measured by US, equation B) and 8.9 ± 4.5 mL (measured by US, equation C), respectively. Only the mean size measured by US and volume calculated with Hansen equation) and the mean size measured by US and volume calculated with Lambert equation) showed no significant difference (mean difference 0.81 mL, P= 0.053 and 0.81 mL, P= 0.056, respectively). Based on our measurements, we categorized testicular volume by different cut-off values (7.0 mL, 7.5 mL, 8.0 mL, and 8.5 mL) to calculate a new constant for use in the Hansen's equation. The new constant was 0.59. We then reexamined the equations using the new 0.59 constant, and found the equation V = L x W2 x 0.59 was the best for describing the testicular volume among our subjects (difference 0.19 mL, P= 0.726). We also found that US was more precise in measuring testicular dimensions. We proposed a new formula V = L x W2 x 0.59 to assess the volumes of smaller testes.
Key words: Testis
orchidometer
testicular volume
ultrasonography
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