Journal of Andrology
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Published-Ahead-of-Print June 2, 2006, DOI:10.2164/jandrol.106.000224

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Production of beta-hCG by spermatic cord leiomyosarcoma: A paraneoplastic syndrome?

Shih-Ming Ou , Shang-Sen Lee , Yi-Jen Peng , Lai-Fa Sheu , Nai-Shun Yao , and Sun-Yran Chang *

* To whom correspondence should be addressed. E-mail: vins1023{at}ndmctsgh.edu.tw.

Spermatic cord leiomyosarcoma is an extremely rare disease, with a high likelihood of locoregional recurrence. Radical inguinal orchiectomy with wide excision of surrounding soft tissue is the choice of treatment. We report a patient with spermatic cord leiomyosarcoma that could be interpreted as a paraneoplastic syndrome, with increased serum beta human chorionic gonadotropin (beta-hCG), and beta-hCG in the tumor demonstrated by immunohistochemistry stain. We suggest that beta-hCG could be used as a biological marker in selective cases of spermatic cord leiomyosarcoma.


Key words: Spermatic cord • Leiomyosarcoma • Beta-hCG






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