Journal of Andrology
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Published-Ahead-of-Print December 8, 2005, DOI:10.2164/jandrol.04191

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Factors affecting the increased prevalence of erectile dysfunction in Greek hypertensive compared to normotensive subjects

Michael Doumas *, Alexandros Tsakiris , Stella Douma , Alkiviadis Grigorakis , Angelos Papadopoulos , Athina Hounta , Sotirios Tsiodras , Dimitrios Dimitrious , and Helen Giamarellou

* To whom correspondence should be addressed. E-mail: michalisdoumas{at}yahoo.co.uk.

Arterial hypertension is considered a risk factor for erectile dysfunction. The aim of the study was to evaluate the prevalence of erectile dysfunction in hypertensive compared to normotensive individuals of similar demographic characteristics in Greece. Furthermore, to investigate the effect of age, hypertension severity, hypertension duration, and antihypertensive medication on erectile function of these subjects. The study population consisted of 634 consecutive young and middle-aged men (31-65 years) that visited our outpatient clinic. From them, 358 patients had arterial hypertension and 276 were normotensive. Erectile dysfunction was evaluated using the International Index for Erectile Function (IIEF questionnaire). Erectile dysfunction was found in 35.2% of patients with essential hypertension compared to 14.1% of normotensive subjects (x2=35.92, p<0.001). Patients with essential hypertension had more severe erectile dysfunction than their normotensive counterparts (x2=17.1, p<0.001). Hypertension duration, hypertension severity, antihypertensive medication and age were positively correlated with erectile dysfunction. The prevalence of erectile dysfunction is higher in patients with essential hypertension compared to normotensive subjects of similar demographic characteristics. Erectile dysfunction is related to age in both groups, while duration and severity of hypertension as well as antihypertensive drugs affect erectile function of hypertensive patients. Erectile dysfunction affects patients' quality of life, underlining the need for vigorous search of this condition and appropriate management.




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