Variable
|
ORa (95% CI)
|
P
|
| Age-adjusted log(total estradiol), pmol/L |
2.69 (1.38-5.24) |
.004 |
| Age-adjusted log(free estradiol), pmol/L |
3.35 (1.84-6.07) |
<.0001 |
| Model 1 |
|
|
| Log(total estradiol), pmol/L |
2.31 (1.39-4.70) |
.02 |
| Log(free estradiol), pmol/L |
2.69 (1.38-5.24) |
<.001 |
| Model 2 [Model 1 + BMI + log(SHBG) + total testosterone + log(DHEAS)] |
|
|
| Log(total estradiol), pmol/L |
2.61 (0.96-6.85) |
.053 |
| Log(free estradiol), pmol/L |
2.59 (1.01-6.66) |
.048 |
| Model 3 (Model 1 + BMI) |
|
|
| Log(total estradiol), pmol/L |
1.79 (0.77-4.09) |
.18 |
Log(free estradiol), pmol/L
|
2.11 (1.03-4.33)
|
.041
|
|
| Abbreviations: BMI, body mass index; 95% CI, 95% confidence interval; DHEAS,
dehydroepiandrosterone sulphate; OR, odd ratio; SHBG, sex
hormone—binding globulin. |
| a Each line refers to the results of a separate model. Values were adjusted
for age, smoking, alcohol, physical activity, log(interleukin-6), and
log(insulin) (Model 1). |
