Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Right arrow Help viewing high resolution images
Right arrow Return to article

Figure 1


Figure. Model for maintenance and differentiation of fetal Leydig cells in mice: SF1+/3βHSD– progenitor cells are transformed into fetal Leydig cells (SF+/3βHSD+) in response to Sertoli cell–derived Hedgehog ligands (Hh). The fetal Leydig cells eventually lose SF1 expression in fetal life and then steroidogenic ability in adulthood. A subpopulation of the progenitor cells is prevented from entering differentiation model via the Notch pathway. The progenitor cell status is putatively maintained as a result of POD1, which down-regulates SF1 expression. Color figure available online at www.andrologyjournal.org.





Right arrow Return to article

HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS