Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Table 2. Spermatogonial differentiation in testes of jsd and SCARKO-jsd mice as measured by the tubule differentiation indexa (TDI) and the effects of hormone treatment on the TDI
    No Treatment   GnRH Antagonist + Flutamide   GnRH Antagonist + Testosterone

  Jsd   6.3 ± 4.8   34.1 ± 9.8b   4.3 ± 0.6c
  SCARKO-jsd   7.0 ± 3.3   55.3 ± 7.7b   5.9 ± 2.1c

  aThe TDI is defined as the percentage of tubules that contain 3 or more differentiating germ cells at the B spermatogonial stage or beyond.
  bTreated mice were significantly different from untreated mice of same genotype.
  cMice treated with GnRH antagonist + testosterone were significantly different from mice of same genotype treated with GnRH antagonist + flutamide.





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