Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Table 10. List of studies using hormonal therapies to increase sperm retrieval for ICSI/IVF
  Condition (No. of Subjects)     Pregnancy, %
 
  Treatment   Treatment Group   Placebo Group   Reference

  Abnormal spermatozoa and failure of IVF (77)   Testosterone undecanoate   17   32   Comhaire et al, 1995
  Azoospermia caused by hypogonadotropic hypogonadism (25)   hCG and FSH   67   —   Bakircioglu et al, 2007
  Oligoasthenoteratozoospermia (18)   hMG   —   —   Beretta et al, 2005
  Oligoasthenoteratozoospermia (23)   R-hFSH, 150 IU for 3 months   30   0/10   Caroppo et al, 2003b
  Oligoasthenozoospermia (24)   FSH   33   20   Baccetti et al, 2004
  Severe oligozoospermia (78)   pFSH (75 IU FSH, <1 IU LH) for ≥50 days   36   18   Ashkenazi et al, 1999
  Idiopathic, severe oligoteratoasthenospermia (76)   pFSH   33   —   Dirnfeld et al, 2000
  Oligoteratoasthenozoospermia (40)   FSH   20   —   Ben-Rafael et al, 2000

  Abbreviations: FSH, follicle-stimulating hormone; hCG, human chorionic gonadotropin; hMG, human menopausal gonadotropin; ICSI, intracytoplasmic sperm injection; IVF, in vitro fertilization; LH, luteinizing hormone; pFSH, purified FSH; R-hFSH, recombinant human FSH.





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