
Figure 5. Effects on progeny outcome after paternal treatment with vehicle (black
bars) and 0.33x BEP (bleomycin, etoposide, and cisplatin; dark-grey
bars) and during the recovery period. Parameters measured were (A)
preimplantation loss, (B) postimplantation loss, (C) average number of pups
per litter, and (D) sex ratios. Preimplantation loss was determined by
calculating the difference between the number of corpora lutea and
implantation sites for each female. Postimplantation loss was determined by
calculating the difference between the number of implantation sites and the
number of live fetuses. Bars represent mean ± SEM; n =
10–15/group; * indicates P < .05.