| |
Adjusted Coefficients, Excluding Sperm Concentration (95% CI)
|
Adjusted Coefficients, Including Sperm Concentration (95% CI)
|
| |
Comet extent |
TDM |
Tail% |
CHDc |
Comet Extent |
TDM |
Tail% |
CHDc |
|
| FSH |
6.61 (1.99, 11.3) |
2.06 (0.27, 3.86)d |
1.90 (-0.02, 3.83)e |
0.19 (0.02, 0.36)d |
2.13 (-2.75, 7.01) |
0.68 (-1.24, 2.59) |
0.97 (-1.11, 3.04) |
-0.01 (-0.19, 0.17) |
| LH |
3.49 (-2.24, 9.20) |
2.45 (0.25, 4.65)d |
-2.22 (-4.58, 0.15)e |
0.24 (0.03, 0.46)d |
0.27 (-5.38, 5.92) |
1.51 (-0.69, 3.72) |
-3.07 (-5.46, -0.70)d |
0.12 (-0.09, 0.33) |
| Inhibin B |
-2.81 (-6.81, 1.18) |
-1.41 (-2.96, 0.11)e |
2.59 (0.96, 4.29)d |
-0.29 (-0.44, -0.14)d |
0.03 (-4.00, 4.07) |
-0.59 (-2.15, 0.96) |
3.48 (1.85, 5.18)d |
-0.19 (-0.33, -0.04)d |
| SHBG |
-0.43 (-5.72, 4.88) |
-0.58 (-2.63, 1.47) |
0.21 (-1.98, 2.40) |
-0.01 (-0.20, 0.20) |
-0.99 (-6.09, 4.11) |
-0.75 (-2.75, 1.25) |
0.09 (-2.08, 2.26) |
-0.03 (-0.22, 0.16) |
| Ta |
2.52 (-4.14, 9.18) |
2.34 (-0.22, 4.86)e |
-4.86 (-7.56, -2.16)d |
0.12 (-0.13, 0.36) |
2.52 (-3.78, 8.82) |
2.34 (-0.14, 4.86)e |
-4.86 (-7.38, -2.16)d |
0.12 (-0.12, 0.36) |
| T:LH |
-2.53 (-7.88, 2.81) |
-1.49 (-3.55, 0.57) |
-0.23 (-2.44, 1.98) |
-0.18 (-0.38, 0.02)e |
0.03 (-0.086, 0.15) |
-0.009 (-0.06, 0.04) |
0.007 (-0.04, 0.06) |
-0.001 (-0.01, 0.003) |
| FAI |
1.40 (-4.13, 6.91) |
1.69 (-0.44, 3.81) |
-3.20 (-5.46, -0.95)d |
0.06 (-0.14, 0.27) |
1.84 (-3.47, 7.15) |
1.82 (-0.25, 3.89)e |
-3.11 (-5.37, -0.87)d |
0.08 (-0.12, 0.28) |
| Estradiola |
-8.71 (-13.4, -4.03)d |
-2.34 (-4.16, -0.52)d |
-4.68 (-6.50, -2.73)d |
0.07 (-0.10, 0.25) |
-8.19 (-12.7, -3.77)d |
-2.21 (-4.03, -0.39)d |
-4.55 (-6.37, -2.60)d |
0.10 (-0.07, 0.26) |
| Prolactin |
-1.90 (-7.60, 3.82) |
-0.74 (-2.95, 1.48) |
1.00 (-1.36, 3.37) |
-0.10 (-0.31, 0.11) |
-3.34 (-8.86, 2.18) |
-1.18 (-3.34, 0.98) |
0.69 (-1.66, 3.05) |
-0.16 (-0.36, 0.04) |
| Free T4 |
-5.67 (-10.8, -0.52)d |
-0.57 (-2.57, 1.44) |
-7.14 (-9.15, -5.13)d |
0.24 (0.05, 0.43)d |
-4.68 (-9.66, 0.29)e |
-0.26 (-2.21, 1.70) |
-6.93 (-8.94, -4.95)d |
0.28 (0.10, 0.47)d |
| Total T3 |
5.70 (-0.11, 11.5)e |
2.25 (0.01, 4.50)d |
-1.07 (-3.48, 1.34) |
0.29 (0.07, 0.50)d |
-3.90 (-8.05, 0.24)e |
-0.21 (-1.85, 1.42) |
-5.78 (-7.45, -4.13)d |
0.24 (0.08, 0.39)d |
| TSH |
0.23 (-4.17, 4.62) |
-0.04 (-1.74, 1.65) |
0.67 (-1.14, 2.49) |
0.05 (-0.11, 0.22) |
-0.25 (-4.47, 3.97) |
-0.19 (-1.84, 1.47) |
0.57 (-1.23, 2.36) |
0.03 (-0.12, 0.19) |
|
| Abbreviations: CHD indicates comets with high DNA damage; CI, confidence
intervals; FAI, free androgen index; FSH, follicle-stimulating hormone; IU,
international units; LH, luteinizing hormone; SHBG, sex hormone—binding
globulin; T, testosterone; TDM, tail-distributed moment; TSH,
thyroid-stimulating hormone. |
| aAll testosterone and estradiol models were also adjusted for SHBG. |
| bAdjusted for age, body mass index, abstinence period, current smoking, season
(winter vs other), and time (morning vs afternoon) of blood sample. |
| cVariable was arcsine transformed. |
| dP < 0.05 |
| eP < .1. |
|
