| |
Relaxation Induced, % (precontraction with 100 µM phenylephrine)
|
|
| Group |
Phenylephrine (100 µM) |
EFS (32 Hz) |
ATP (2 mM) |
Acetylcholine (500 µM) |
SNP (100 µM) |
SM:Collagen Ratio |
|
| C |
15.73 ± 1.84 |
88.80 ± 14.39 |
33.96 ± 6.32 |
22.78 ± 7.9 |
53.36 ± 9.02 |
5.01 ± 0.42 |
| O |
9.78 ± 1.3b |
45.50 ± 16.87b |
23.77 ± 1.70b |
7.37 ± 2.27b |
34.01 ± 5.81b |
3.32 ± 0.36b |
| R4 |
10.86 ± 1.76b |
43.08 ± 10.89b |
25.86 ± 8.9b |
8.40 ± 2.8b |
40.27 ± 8.65b |
3.57 ± 0.66b |
| R8 |
10.66 ± 1.26b |
72.10 ± 11.4b,c |
23.86 ± 5.81b |
14.11 ± 4.18b,c |
43.62 ± 3.58b,c |
3.43 ± 0.23b |
|
| Abbreviations: C indicates control; EFS, electrical field stimulation; O,
obstruction; R4, reversal for 4 weeks; R8, reversal for 8 weeks; SM, smooth
muscle; and SNP, sodium nitroprusside. |
| aEach number represents the mean ± SEM of 6 individual rabbits. |
| bSignificantly different than control group; P < .05. |
| cSignificantly different than obstruction group; P < .05. |
|
