| |
Testosterone Gel (9-mo treatment)
|
Testosterone Undecanoate (9-mo treatment)
|
| |
Reference range |
Baseline |
9 Mo |
Change, % |
Baseline |
9 Mo |
Change, % |
|
| Testosterone, ng/mL |
3.0-8.6 |
2.2 ± 0.4 |
3.6 ± 0.8 |
63.64 |
2.2 ± 0.6 |
5.3 ± 0.7 |
140.91 |
| SHBG, nmol/L |
10-73 |
39 ± 20 |
31 ± 15 |
-20.51 |
28.0 ± 16.0 |
29.0 ± 11.0 |
3.57 |
| IIEF |
NA |
12.0 ± 2.6 |
17.0 ± 5.3 |
41.67 |
7.4 ± 1.9 |
18.9 ± 7.8 |
155.41 |
| AMS |
NA |
48.3 ± 4.4 |
31.1 ± 4.9 |
-35.61 |
50.0 ± 4.8 |
31.0 ± 2.9 |
-38.00 |
| Waist circumference, cm |
NA |
107.8 ± 9.4 |
105.5 ± 8.7 |
-2.13 |
102.0 ± 11.0 |
99.0 ± 11.0 |
-2.94 |
| Weight, kg |
NA |
92.3 ± 7.8 |
91.0 ± 7.9 |
|
88 ± 6.9 |
87 ± 5.6 |
|
| Total cholesterol mg/dL |
<220 |
263.0 ± 32.0 |
227.0 ± 26.0 |
-13.69 |
268.0 ± 40.0 |
207.0 ± 25.0 |
-22.76 |
| LDL, mg/dL |
<150 |
168.0 ± 12.0 |
150.0 ± 7.0 |
-10.71 |
164.0 ± 26.0 |
134.0 ± 29.0 |
-18.29 |
| Triglycerides, mg/dL |
<180 |
249.0 ± 47.0 |
212.0 ± 30.0 |
-14.86 |
312.0 ± 76.0 |
195.0 ± 72.0 |
-37.50 |
| HDL, mg/dL |
>150 |
33.0 ± 5.0 |
36.0 ± 5.0 |
9.09 |
36.5 ± 13.7 |
45.6 ± 11.7 |
24.93 |
| Systolic BP, mm Hg |
120 |
144.0 ± 13.0 |
144.0 ± 15.0 |
|
148.0 ± 18.0 |
146.0 ± 18.0 |
-1.35 |
| Diastolic BP, mm Hg |
80 |
77.0 ± 8.4 |
78.0 ± 5.6 |
|
80.0 ± 9.0 |
77.0 ± 6.0 |
-3.750 |
| Glucose, mg/dL |
70-110 |
98.0 ± 23.0 |
92.0 ± 13.0 |
|
105.0 ± 30.0 |
100.0 ± 18 |
|
| Hemoglobin, g/dL |
13.3-17.7 |
14.0 ± 0.8 |
15.0 ± 0.7 |
7.14 |
14.3 ± 1.3 |
15.3 ± 0.8 |
6.99 |
| Hematocrit, % |
40-52 |
40.0 ± 3.0 |
45.0 ± 3.0 |
12.5 |
41.3 ± 5.6 |
46.4 ± 3.0 |
12.35 |
| PSA, µg/L |
<4.0 |
1.2 ± 0.8 |
1.1 ± 0.8 |
|
2.0 ± 0.8 |
2.0 ± 0.9 |
|
| IPSS |
|
15.2 ± 3.5 |
13.7 ± 3.5 |
-9.87 |
13.4 ± 2.8 |
11.7 ± 3.0 |
-12.69 |
|
| *AMS, aging male scale; BP, blood pressure; HDL, high-density lipoprotein;
IIEF, international index of erectile function; IPSS, international prostate
symptoms score; LDL, low-density lipoprotein; NA, not applicable; PSA,
prostate-specific antigen; and SHBG, sex hormone—binding globulin. |
| % change at 9 months vs baseline P < .05. |
| % change TU (9 mo) > T gel (9 mo) P < .05. |
|
