| |
TNF- (pg/mL) |
IL-6 (pg/mL) |
IL-1ß (pg/mL) |
Sperm Motility, Untreated (%) |
Sperm Motility, Treated (%) |
|
| SCI case no. |
|
|
|
|
|
| SCI 1 |
59.2 |
132.0 |
43.0 |
33 |
52 |
| SCI 2 |
3.0 |
13.0 |
6.0 |
18 |
20 |
| SCI 3 |
244.4 |
11.0 |
36.0 |
19 |
49 |
| SCI 4 |
3.6 |
428.0 |
44.0 |
19 |
34 |
| SCI 5 |
Undetectable |
56.5 |
33.0 |
15 |
21 |
| SCI 6 |
14.4 |
103.2 |
Undetectable |
41 |
49 |
| SCI 7 |
245.0 |
101.4 |
11.3 |
11 |
34 |
| SCI 8 |
58.3 |
623.0 |
50.2 |
0 |
7 |
| SCI 9 |
104.2 |
320.5 |
Undetectable |
17 |
42 |
| SCI 10 |
3.0 |
428.0 |
28.3 |
15 |
34 |
| SCI 11 |
247.0 |
58.0 |
3.8 |
4 |
29 |
| Control case no. |
|
|
|
|
|
| Control 1 |
Undetectable |
3.6 |
5.1 |
52 |
52 |
| Control 2 |
Undetectable |
8.2 |
4.0 |
56 |
54 |
| Control 3 |
Undetectable |
5.7 |
3.6 |
51 |
54 |
| Control 4 |
Undetectable |
12.1 |
5.0 |
52 |
55 |
| Control 5 |
Undetectable |
9.0 |
2.1 |
58 |
54 |
|
| *The table shows concentrations of the cytokines tumor necrosis factor-
(TNF-), interleukin-6 (IL-6), and IL-1ß in the seminal plasma of
SCI and control subjects |
| Expected seminal plasma values for healthy men: TNF-: less than
5 pg/mL; IL-6, 4–15 pg/mL; IL-1ß, 1–5 pg/mL |
| Sperm motility (%) is shown before and after treatment with
neutralizing agents to these cytokines. Sperm motility (untreated) indicates %
sperm motility before treatment with agents to neutralize activity of
TNF-, IL-6, and IL-1ß at the receptor level; sperm motility
(treated), % sperm motility after treatment with agents to neutralize activity
of TNF-, IL-6, and IL-1ß at the receptor level |
|
