Recipient Rat No. |
Donor |
Testis wt (mg) Right/Left |
Days From Transplant to First Pup |
Days From Transplant to First Transgenic Pup |
Transgenic/Total Progeny (%) |
|
A1718 |
MT LacZ |
NA/196 |
NA |
NA |
0/0 |
| A1719 |
MT LacZ |
386/NA |
147 |
207 |
1/14 (7.1) |
| A1800 |
MT LacZ |
580/710 |
120 |
180 |
7/178 (3.9) |
| A1913 |
S/D |
486/721 |
NA |
NA |
0/0 |
| A1914 |
S/D |
631/1199 |
123 |
254 |
2/51 (3.9) |
| A1943|| |
S/D |
NA/NA |
112 |
140 |
4/159 (2.5) |
| A1944 |
S/D |
1038/1474 |
147 |
256 |
1/15 (6.7) |
| A1945 |
S/D |
418/1208 |
120 |
232 |
1/76 (1.3) |
| A2107|| |
S/D |
NA/NA |
103 |
157 |
10/119 (8.4) |
| A2108 |
S/D |
539/747 |
104 |
104 |
16/118 (13.6) |
| Total |
|
|
|
|
42/730 (5.8) |
|
| * MT indicates metallothionein I; N/A, not available; and S/D, Sprague-Dawley. |
| Recipient rats were treated with busulfan (10 mg/kg) at 8-10 dpp and
used for transplantation between 18 and 22 days of age. |
| Testis weights were determined at the end of the breeding period
(13-23 months of age). |
| Recipient A1718 had only 1 testis. |
| || Died before testis weight could be recorded. |
