Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Table 2. 5-HT–mediated contraction of human cavernosal tissues before (control) and after the addition of a chemical agent (antagonist or distilled water [vehicle]). Results are presented as median (range) in mg tension/mg of tissue. N denotes number of patients studied. Wilcoxon test is used for statistical analysis. Significance is described as P < .05
  Control   Antagonist   Treatment   N   P value

  49.9 (7.8-179.5)   8.0 (1.7-24.1)   10-6 M Doxazosin   10   < .02
  59.8 (10.1-84.6)   3.4 (0-30.9)   10-4 M Doxazosin   8   < .02
  97.5 (25.3-205)   99.4 (27.9-173)   10-5 M Corynanthine   13   > .1
  91.2 (26.6-230.1)   93.7 (35.8-242.6)   10-5 M Yohimbine   9   > .1





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