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Perspectives and Editorials |
I respectfully submit that this is inaccurate. TESE is, from a surgical
point of view, little more than a testis biopsy, and in my
26 years at
our institution doing this in dozens of patients, save for one or two who
requested general anesthesia because of perceived testisphobia (sic), I don't
recall ever doing a TESE, regardless of whether it was multifocal (sometimes
up to 6+ biopsies per testis) or unifocal, under general anesthesia and in an
operating suite. In fact, at UCLA it would cost almost as much as many IVF
centers charge for ICSI/IVF if I were to do a testis biopsy in the operating
suiteand this does not include the surgical fee for the TESE. Cost is
therefore one of a number of reasons why TESE is done under local anesthesia
in the office setting. With TESE, complete anesthesia of the area, whether
unilateral or bilateral, can be obtained by an intradermally injected
anesthetic plus a cord block. While a few of our patients undergoing TESE have
had a vasovagal reflex which simply responded to intranasal ammonia, we have
never lost a testis nor had a complication of the cord block that necessitated
any corrective therapy.
I for one have always assumed that those physicians who did TESA did so because they were primarily andrologists and were, therefore, not surgically trained. While this may be true or not, based on the powerful data of these two excellent studies, it seems prudent that those who perform TESA in preference to TESE need to rethink their reasons for ever considering TESA as a method of sperm aspiration, particularly in nonobstructive azoospermia.
Respectfully yours, Jacob Rajfer, MD
Footnotes
References
Hauser R, Yogev L, Paz G, Yavetz H, Azem F, Lessing JB, Botchan A.
Comparison of efficacy of two techniques for testicular sperm retrieval in
nonobstructive azoospermia: multifocal testicular sperm extraction versus
multifocal testicular sperm aspiration. J Androl. 2006; 27: 28
33.
Kova
i
B, Vlaisavljevi
V, Relji
M.
Clinical use of pentoxifylline for activation of immotile testicular sperm
before ICSI in patients with azoospermia. J Androl. 2006; 27: 45
52.
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