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Table 4.
Development of immature rat donor germ cells in recipient mouse testes 13 weeks after transplantation
*
Treatment Group
No. of Testes
Weight per Testis (mg)
Total Tubule Differentiation Index (%)
Viable Cells Injected per Testis (
x
10
4
)
Tubule Cross-Sections That Were GFP-Positive (%)
GFP-Positive Tubule Cross-Sections With Differentiated Germ Cells (%)
Irradiation
*
14
47 ± 3
69 ± 4
76 ± 7
35 ± 5
76 ± 4
Busulfan
8
90 ± 16
93 ± 2
67 ± 10
16 ± 5
36 ± 10
*Treatment consisted of 1.5 + 12 Gy administered 24 hours apart
Treatment consisted of a 44-mg/kg dose
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