| Study |
n |
High DFI Predicts Low Pregnancy Rate in IVF/ICSI? |
DFI Cutoff (%) |
Low DFI, Pregnant/Total |
High DFI, Pregnant/Total |
|
| Larson et al, 2000 |
21 |
Yes |
27 |
7/12 |
0/9 |
| Larson-Cook et al, 2003 |
89 |
Yes |
27 |
28/79 |
0/10 |
| Saleh et al, 2003* |
14* |
Yes |
27 |
N/A* |
N/A* |
Bungum et al, 2004 |
175 |
No |
27 |
47/140 |
13/35 |
| Gandini et al, 2004 |
34 |
No |
27 |
7/24 |
5/10 |
| Virro et al, 2004 |
249 |
Yes |
30 |
84/178 |
20/71 |
Chohan et al, 2004 |
52 |
Trend |
30 |
25/43 |
4/9 |
Gardner et al,
2004* |
128* |
No |
30 |
35%* |
37%* |
| Adams et al, 2004 |
50 |
Yes |
30 |
30/41 |
2/9 |
| Nicopoullos et al,
2005* |
37* |
Trend |
15 |
50%* |
26%* |
| Payne et al, 2005 |
98 |
No |
27 |
22/79 |
9/19 |
| Check et al, 2005|| |
106 |
No|| |
30 |
26/77 |
8/29 |
| Zini et al, 2005 |
60 |
No |
30 |
25/49 |
6/11 |
| Total |
929 |
|
|
301/722 (42%) |
67/212 (31%) |
|
| *Could not obtain actual patient numbers to include in total |
| A statistically nonsignificant trend toward low pregnancy rates in
high-DFI patients was seen in the conventional IVF group, but not ICSI
subgroup. Statistically significant difference between DFI groups seen in IUI
patients |
| Conference abstract only |
| Numbers shown are for implantation rate |
| ||Numbers reported are for clinical pregnancy. There was a statistically
nonsignificant trend for lower ongoing pregnancy in the high-DFI group |
|
