| |
Duration of Treatment |
| |
6 wk |
9 wk |
| |
Control |
BEP |
Control |
BEP |
|
| Litter size |
14.61 ± 0.54 |
14.50 ± 0.73 |
13.53 ± 1.19 |
12.54 ± 0.82 |
| Preimplantation loss |
0.05 ± 0.02 |
0.09 ± 0.03 |
0.15 ± 0.06 |
0.17 ± 0.04 |
| Postimplantation loss |
0.01 ± 0.02 |
0.02 ± 0.06 |
0.07 ± 0.02 |
0.11 ± 0.04 |
| Sex-ratio |
0.48 ± 0.03 |
0.49 ± 0.04 |
0.50 ± 0.03 |
0.39 ± 0.05 |
|
| *BEP indicates bleomycin, etoposide, and cis-platinum treatment, as defined in
the "Materials and Methods" section. 6 Weeks: control, n = 18;
BEP, n = 12; 9 Weeks: control, n = 15; BEP, n = 11. Preimplantation loss is
defined as the number of corpora lutea minus the number of implantation sites
per litter. Postimplantation loss is defined as the number of implantation
sites minus the number of fetus per litter on day 20 of gestation |
| All values are expressed as the mean ± SEM |
|
