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Table 4. Calculation of the statistical parameters of the determination of azoospermia for (NAG; -glucoside 20 mU/ejaculate) as differentiation criterion. For the calculation, a distinction was made between spring, autumn, and all data obtained throughout the year. The seasonal difference for the prevalence of azoospermia and the positive predictive value of the test is obvious. The prevalence for summer and winter would be 17.6% and 15.7%, respectively

Parameter   All Data   Spring   Autumn   Positive group (n)   74   12   27   Prevalence (%)   15.7   9.38   20.5   Area under ROC curve*   0.733   0.787   0.727   Calculated cut-off (million sperm/mL)   0   0   0.4   Sensitivity (%)   59.5   66.7   63.0   Specificity (%)   83.3   82.8   79.0   Positive predictive value (%)   40.0   28.6   43.6   Negative predictive value (%)   91.7   96.0   89.2   *ROC indicates receiving operating instructions

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