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Table 3. Changes in leptin and body mass index (BMI)^*

	Leptin, ng/mL		BMI, kg/m²
	Baseline	Day 28-30 ${dagger}$	Baseline	Day 28-30 ${dagger}$

Study 1
Acyline	5.9 ± 1.0	8.4 ± 1.3 ${ddagger}$	26.0 ± 0.8	26.2 ± 0.8
Acyline + TE	2.2 ± 0.5	2.6 ± 0.6	23.7 ± 0.9	23.7 ± 0.9
	Baseline	Day 21	Baseline	Day 21
Study 2
Placebo	8.5 ± 1.2	9.7 ± 1.2 ${ddagger}$	32.5 ± 1.6	32.3 ± 1.3
TE 600 mg/wk IM	9.1 ± 1.4	6.1 ± 0.9 ${ddagger}$ $§$	30.1 ± 1.6	31.0 ± 1.6 ${ddagger}$ $§$

*TE indicates testosterone enanthate.
${dagger}$ Leptin and BMI were measured on day 28 in the group receiving Acyline + TE and day 30 in the groups receiving Acyline alone.
${ddagger}$ P < .05 vs baseline.
$§$ P < .05 vs placebo.