Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Table 2. Examples of candidate early development antisense RNAs identified in sperm*
  Gene ID   Chromosomal Location   Tissue Distribution

  CACNA1G   17q21.33   Brain, amygdala, subthalamic nuclei, cerebellum, thalamus, heart, placenta, kidney, lung, colon, bone marrow, fetal brain, fetal heart, fetal kidney, fetal lung
  PRO-NRG3   10q23.1   Brain, testis, aorta, hypothalamus, fetal brain, retina, cochlea, MS, neuroblastoma
  ALS2CR17   2q33.2   Fetal eye, lung, pancreas, placenta, chondrosarcoma
  LTBP1   2p22.3   Fibroblasts, breast adenocarcinoma, LCIS, bone, whole embryo, amygdala, kidney, ovary, chondrosarcoma, lung tumor
  DKK2   4q25   Heart, brain, skeletal muscle, lung, placenta, cochlea, Ewings sarcoma, meningioma, fetal heart, pregnant uterus, melanocyte, leiomyosarcoma
  SCL26A7   8q21.3   Thymus, testis, osteoblastic cells, clear cell tumor, placenta, endometrial adenocarcinoma, fetal eyes, eyes, pancreatic islet
  IGF2R   6q25.3   Fetal pancreas, invasive carcinoma, lymphoma, spinal cord, anterior eye, myeloid cells, uterus, lens, optic nerve, peripheral nervous system
  KIAA1576   16q23.1   Brain, DRG, astrocytoma, sympathetic trunk, retina, iris, RPE, adrenal adenoma, teratocarcinoma, lens, embryonal carcinoma, placenta, embryonic stem cells
  FAT3   11q14.3   Wilms, brain, bone, hypothalamus, chondrosarcoma, melanocyte, fetal heart, pregnant uterus, lung, thymus, spleen, spinal cord, mammary gland, liver, intestines, skeletal muscle, kidney, heart
  COG7   16p12.2   Prostate, brain, adrenal adenoma, renal cell adenoma, placenta, optic nerve, NK cells, sciatic nerve, neuroblastoma
  HNT   11q25   Brain, oligodendroglioma, fetal eyes, eyes, optic nerve, retina, carcinoid, hippocampus, schizophrenic brain, amelanotic melanoma
  TIA1   2p13.3   Carcinoma, adenocarcinoma, wilm's tumor, kidney, leukopheresis, thymus, whole embryo, malignant melanoma, uterus, hypothalamus
  ISL1   5q11.2   Retina, adenocarcinoma, neuroblastoma, fetal eyes, optic nerve, testis, placenta, insulinoma, adrenal medulla, dorsal root ganglion, pineal, brain
  ZNF462   9q32   Kidney, early stage papillary serous carcinoma, posterior rhombomeres, mandible, Ewings sarcomamelanotic melanoma, colonic mucosa, aleolar rhabdomyosarcoma, fetal eyes, human retina, embryonic stem cells, testis
  CHUK   10q24-q25   Normal endometrium, myelogenous leukemia, neuroblastoma, meningiomas, uterine, human retina, sciatic nerve, RPE and Choroid, placenta, adrenal cortex carcinoma

  *For additional information, see http://compbio.med.wayne.edu/Sperm_RNAi.htm. Tissues representative of early development are italicized.





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