Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Mitotic and meiotic structural maintenance of chromosome (SMS) and associated proteins in vertebrates*
  Mitosis
  Meiosis
  Protein   Complex   Function   Protein   Complex   Function

  SMC1   Cohesin   SCC, Rec Rep   SMC1{alpha}   Cohesin   SCC, ?
        SMC1ß   Cohesin   SCC, Rec, Chr Struct
  SMC3   Cohesin   SCC, Rec Rep   SMC3   Cohesin   SCC, Rec, Chr Struct
  RAD21   Cohesin   SCC, Rec Rep   RAD21   Cohesin   SCC, ?
        REC8   Cohesin   SCC, ?
  SA1 or SA2   Cohesin   SCC, ?   STAG3   Cohesin   SCC, ?
  SMC2   Condensin   M Chr Struct   SMC2   Condensin   M Chr Struct
  SMC4   Condensin   M Chr Struct   SMC4   Condensin   M Chr Struct
  CAP-D2   Condensin   M Chr Struct   ?   Condensin   M Chr Struct
  CAP-G   Condensin   M Chr Struct   ?   Condensin   M Chr Struct
  CAP-H   Condensin   M Chr Struct   ?   Condensin   M Chr Struct
  CAP-D3   Condensin II   M Chr Struct   ?   Condensin   M Chr Struct
  CAP-H2   Condensin II   M Chr Struct   ?   Condensin   M Chr Struct
  CAP-G2   Condensin II   M Chr Struct   ?   Condensin   M Chr Struct
  SMC5     DNA repair   SMC5   ?   ?
  SMC6     DNA repair   SMC6   ?   ?
  Nse1     DNA repair   ?    
  Nse2     DNA repair   ?    
  Nse3     DNA repair       Meiotic segregation, Rec
  RAD60     DNA repair   ?    

  *The same SMC protein might be involved in several different complexes with related or different functions; only the most prominent is named; several different cohesion complexes exist in meiotic cells. The same complex or protein might have different functions; only functions for which there is significant evidence are indicated. SCC indicates sister chromatid cohesion; Rec Rep, recombinational repair; Rec, recombination; M Chr Struct, metaphase chromosome structure; Chr Struct, chromosome structure; ?, unknown but suspected additional proteins, complexes, or functions.





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