Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Differentially expressed genes in dark and light testis tissue of prepubertal colts*
    Dark-Specific

  Signaling Molecules
  3.6   Insulin-like growth factor 2
  3.6   Parathymosin-cell cycle regulated
  2.1   ATP-binding cassette 3
  1.9   CDC-like kinase
  1.9   Major histocompatibility complex, Class 1, B
  1.8   Insulin-like growth factor binding protein 7
  1.8   Protein kinase C, µ
  1.8   Phospolipase D2
  1.8   CD63 antigen (melanoma I antigen)
  1.7   Major histocompatibility complex, Class 1, C
  1.5   Methyl-CPG binding domain protein 3
  1.4   HLA-G histocompatibility antigen, Class 1, G
  Cytoskeleton & Adhesion Molecules
  4.1   Desmoplakin
  3.7   Dysferlin, limb girdled muscular dystrophy{dagger}
  3.0   Laminin, ß1
  2.8   Keratin 8
  2.5   Golgi apparatus protein{dagger}
  2.3   Down-regulating in ovarian cancer 1{dagger}
  2.2   Keratin 18
  2.1   Absent in melanoma
  2.0   Ribosomal proteins L13A & L
  1.9   Crystallin, µ
  1.9   Ribosomal proteins L3 & L6
  1.9   Sarcoglycan
  1.8   Calponin 3, acidic
  1.8   Cadherin 3, Type 1, placental
  1.8   AT-rich sequence binding protein
  1.8   Ribosomal proteins L9, L12, S14
  1.7   Ribosomal proteins P0 & S3, S7, S10, S23
  1.6   Ribosomal protein S15A
  Enzymes & Inhibitors
  2.3   O-linked N-acetylglucosamine transferase
  2.0   Glutathione-S-transferase {Omega}
  1.9   Carboxypeptidase E
  1.9   Argininosuccinate synthetase
  1.8   Protein S (Alpha)
  1.8   Ribonuclease, RNASE A family
  1.8   ATPASE, Na+/K+ transporting, 2 polypeptide
  1.8   Vaccinia-related kinase 1
  1.8   Serine (cysteine) proteinase inhibitor, clade A 5
  1.7   Serine (cysteine) proteinase inhibitor, clade G 1
  1.6   Sterol-C4-methyl oxidase-like
  1.6   Eukaryotic translation elongation factor 1 ß 2
  1.6   Muscleblind (drosophila)-like
  1.5   ESTS, similar to ITF2 Human trans factor 4
  Unknown Function
  2.5   KIAA0018 gene product
  2.1   Hypothetical protein FLJ20030
  2.0   Mesoderm-specific transcript homolog
  1.9   KIAA0202 protein
  1.7   Homo sapiens MRNA clone 2068071
  1.7   KIAA0286 protein

  *Differentially expressed genes in dark and light testis tissues from at least 2 of the 3 horses are shown
  {dagger}Indicates genes differentialy expressed in all 3 horses
  {ddagger}Indicates average of only 2 usable balanced difference values

    Light-Specific

  Signaling Molecules
  -5.0   Cyclin A 1
  -4.4   Phosphodiesterase 3B, CGMP-inhibited{dagger}
  -2.5   STE-20-related kinase
  -2.3   Cell division cycle 2
  -2.2   A kinase (PRKA) protein (Gravin) 12
  -2.2   CBP/P300-interacting transactivator 1
  -2.0   CDC28 protein kinase 2
  -2.0   MAD3L
  -2.0   Guanine nucleotide binding protein, {delta}3
  -1.9   Phospholipase C, {delta} 1
  -1.8   Cholecystokinin
  -1.8   Sortilin 1
  -1.6   Angio-associated, migratory cell protein
  -1.6   Purine-rich element binding protein B
  -1.6   PRKC-prostate apoptosis response protein 4
  Cytoskeleton & Adhesion Molecules
  -7.8   Outer dense fiber of sperm tails 2{dagger}
  -7.7   Protamine 1
  -4.4   Calmegin (Calnexin-t)
  -4.0{ddagger}   Oligodendrocyte transmembrane protein
  -22   Kinesin-like 1
  -1.7   Coctactin 2 (axonal)
  -1.7   Leukemia-associated phosphoprotein P18
  -1.6   Tubulin, {alpha} 1 (testis-specific)
  Enzyme & Inhibitors
  -3.3   Glycerol kinase
  -2.8   Hydroxyacyl glutathione hydrolase
  -2.7{ddagger}   MUTs (E. Coli) homolog 4
  -2.3   Coagulation factor C
  -2.3   Glucose transporter pseudogene
  -2.2   Phosphorylase kinase, {gamma} 2 (testis)
  -1.8   Serine (cyst) proteinase inhibitor, clade F 1
  -1.8   Forkhead box G1B
  Unknown Function
  -2.5   Homo sapiens MRNA; DKFZP434P2072
  -2.3   Interferon, {alpha}-inducible protein (clone IF1616)
  -2.0{ddagger}   KIAA0282 protein
  -1.8   HSPC033 protein

  *Differentially expressed genes in dark and light testis tissues from at least 2 of the 3 horses are shown
  {dagger}Indicates genes differentialy expressed in all 3 horses
  {ddagger}Indicates average of only 2 usable balanced difference values





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