| Parameter |
A1R +/+ |
A1R +/- |
A1R -/- |
|
| A. In vivo fertility |
|
|
|
| Number of litters |
40 |
40 |
40 |
| Average number of pups |
8 ± 2.1 |
8 ± 1.9 |
5 ± 1.7 |
| Birthweight (g) |
2.07 ± 0.8 |
2.05 ± 0.6 |
2.08 ± 0.4 |
| Days between litters |
45 ± 8 |
47 ± 8 |
53 ± 15 |
| B. Reproductive parameters |
|
|
|
| Number of spermatozoa |
13 x 106 ± 2 x 106 |
11 x 106 ± 3 x 106 |
12 x 106 ± 1 x 106 |
| % Viability |
80 ± 10 |
76 ± 7 |
77 ± 9 |
| % Motility |
75 ± 7 |
72 ± 9 |
71 ± 11 |
| C. Phenotype |
|
|
|
| Weight of adult animal (g) |
33 ± 5 |
31 ± 7 |
32 ± 4 |
| Weight of testis (mg) |
132 ± 21 |
121 ± 15 |
122 ± 18 |
|
| *A values are the means ± SEM of 40 litters, P < .05. B and
C values are the means ± SEM of 20 male mice, P < .05. |
|
