Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Figure 3. Sequence analysis of mitochondrial genes of the oligoasthenoteratozoospermic man showed 8 nucleotide substitutions in cytochrome oxidase I, 13 substitutions and 2-bp deletions in cytochrome oxidase II, 5 substitutions in adenosine triphosphate synthase 8 (ATPase8), and 10 substitutions in ATPase6 in sperm mitochondrial DNA (mtDNA). These substitutions created 9 missense mutations, while the rest were silent mutations (*). A 2-bp deletion in cytochrome oxidase II (8195 and 8196) introduced a stop codon (AGA) at 8216, which possibly resulted in a truncated protein.





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