
Figure 6. Schematic depiction of the subunit composition of the KATP and
maxi-K channels (KCa) in corporal smooth muscle. (Panel A):
As illustrated, the
, or pore-forming component of the KATP
channel, is a tetramer of homomeric subunits (stippled; Kir; inward
rectifier). The
subunits are associated in a 1:1 stoichiometry with
homomeric ß subunits (sulfonylurea receptors, SUR; dark semicircles).
(Panel B): As illustrated, the
, or pore-forming component of
the maxi-K channel, is a tetramer of homomeric subunits (gray). The
subunits are associated in a 1:1 stoichiometry with homomeric ß subunits
(dark ovals).