Journal of Andrology Proceedings of the Fifth International Conference on the Epididymis
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Table 3. Mean ± SD of the difference between the placebo and melatonin treatments within the 2 groups of normal men studied*
Nonresponders (n = 6)
 Responders (n = 2)
 t Test
Mean SD Mean SD P value
Sperm concentration -12.2 11.6 20.0 1.4 .01
Sperm motility -0.8 7.1 20.5 12.0 .02
Seminal plasma E2 -1.0 24.6 64.0 9.9 .01
Seminal plasma testosterone 0.0 0.5 -1.2 0.8 .04
Seminal plasma T:E2 0.0 2.4 -6.2 3.7 .03
Serum E2 -12.8 17.0 38.0 2.8 .007
Serum testosterone 0.7 4.8 -0.5 0.7 NS
Serum T:E2 49.7 51.3 -265.0 94.0 .0007
*NS indicates not significant; E2, 17-ß-estradiol (pmol/L); and T, testosterone (nmol/L).





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