Journal of Andrology
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Published-Ahead-of-Print August 12, 2010, DOI:10.2164/jandrol.110.010538

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Live Birth after ICSI of Micro TESE-Retrieved Spermatozoa into In Vitro Matured Oocytes: Case Report

Weon-Young Son *, Jin-Tae Chung , Peter T.K. Chan , and Seang Lin Tan

* To whom correspondence should be addressed. E-mail: weon-young.son{at}muhc.mcgill.ca.

This case report describes a live birth resulting from intracytoplasmic sperm injection (ICSI) of spermatozoa retrieved by microdissection testicular sperm extraction (micro-TESE) into oocytes produced from hCG-primed in vitro maturation (IVM) cycles. In the IVM treatment, a total of 30 oocytes (one mature and 29 immature oocytes) were retrieved. Following IVM, 9 oocytes had matured. A total of four oocytes were fertilized after ICSI with the husband's micro-TESE spermatozoa and four embryos were transferred into the uterus on day 3. A healthy boy weighing 2500 g was born at 35.5 weeks of gestation.


Key words: ICSI • In vitro oocyte maturation • microdissection testicular sperm extraction • non-obstructive azoospermia • polycystic ovaries






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