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* To whom correspondence should be addressed. E-mail: john.mccarrey{at}utsa.edu.
The central theme of the XX North American Testis Workshop, Testicular Function: Levels of Regulation, reflected the many recent discoveries of new and complex levels of regulation of testicular functions. These included regulation of testicular development, including the initial formation of the testis and male germ cells, as well as the subsequent differentiation of key components of the testis, including Sertoli cells, Leydig cells and spermatogenic cells. Many different regulatory mechanisms responsible for these differentiative functions were explored. The roles of genes encoding key regulatory proteins, as well as signal transduction mechanisms, RNA-processing mechanisms, regulation by small non-coding RNAs, and mechanisms governing self-renewal and/or differentiation of spermatogonial stem cells were all discussed in this light. The workshop, which was held at the Hyatt Regency Philadelphia at Penn's Landing in Philadelphia, Pennsylvania from April 1-4, 2009, featured 15 invited talks and six short talks selected from abstracts submitted for the two poster sessions. Manuscripts from 12 of the invited talks are presented in this volume. They are organized into four parts: Regulation of Testis Development, Regulation of Testis Function, Regulation of Germ Cell Development, and Regulation of Gamete Development and Function.
Key words: Testis Workshop
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