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Journal of Andrology, Vol 9, Issue 1 15-20, Copyright © 1988 by The American Society of Andrology

JOURNAL ARTICLE

Morphologic changes induced by short-term ischemia in the rat testis are not affected by treatment with superoxide dismutase and catalase

A. Bergh, J. E. Damber and S. L. Marklund
Department of Pathology, University of Umea, Sweden.

Short-term testicular ischemia was induced unilaterally by ligating the testicular artery for 60 or 100 minutes in adult rats. After 7 days, the rats were fixed by vascular perfusion. The effect of ischemia and reperfusion was quantified using morphometric techniques. Occlusion of the testicular artery for 60 and 100 minutes resulted in a mild and moderate damage, respectively, to the seminiferous tubules. The contralateral control testis was not affected. To study the role of oxygen radicals in ischemia-reperfusion-induced testicular damage, rats were treated with superoxide dismutase and catalase. These radical scavengers did not influence the extent of testicular damage.


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A. Bergh, O. Collin, and E. Lissbrant
Effects of Acute Graded Reductions in Testicular Blood Flow on Testicular Morphology in the Adult Rat
Biol Reprod, January 1, 2001; 64(1): 13 - 20.
[Abstract] [Full Text]


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