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Journal of Andrology, Vol 22, Issue 5 759-763, Copyright © 2001 by The American Society of Andrology

JOURNAL ARTICLE

Does sperm morphology play a significant role in increased sex chromosomal disomy? A comparison between patients with teratozoospermia and OAT by FISH

L. A. Gole, P. F. Wong, P. L. Ng, X. Q. Wang, S. C. Ng and A. Bongso
Department of Obstetrics and Gynecology, National University Hospital, Singapore.

Eight semen samples from men with teratozoospermia (T), along with samples from 3 men with normal fertility and 5 samples from men with oligoasthenoteratozoospermia (OAT) were analyzed for X and Y chromosomal anomalies with the use of fluorescently labeled centromeric probes. This study was undertaken to determine whether patients with abnormal sperm morphology (teratozoospermia) have increased or decreased incidence of a sex chromosomal anomaly. The sex chromosome disomy for the T samples was 0.36% and for the OAT group it was 0.61%, compared with baseline value for the normozoospermia group (0.09%).


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Copyright © 2001 by The American Society of Andrology.