Journal of Andrology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Vollmar, A. M.
Right arrow Articles by Schulz, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Vollmar, A. M.
Right arrow Articles by Schulz, R.

Journal of Andrology, Vol 11, Issue 5 471-475, Copyright © 1990 by The American Society of Andrology

JOURNAL ARTICLE

Atrial natriuretic peptide precursor material in rat testis

A. M. Vollmar, A. Friedrich and R. Schulz
Institute of Pharmacology, Toxicology and Pharmacy, University of Munich, Federal Republic of Germany.

Atrial natriuretic peptide (ANP) has recently been suggested to play a role in the regulation of male reproduction. Specifically, it has been shown to affect steroidogenesis in Leydig cells. The data presented here demonstrate that the rat testis also contains immunoreactive, ANP-like material (IR-ANP). Characterization of this material was conducted by high-pressure liquid chromatography (HPLC) analysis employing two different antisera to recognize either the C- or the N-terminals of the ANP prohormone (ANP 1-126). The IR-ANP corresponded to the 15 kd ANP precursor molecule (ANP 1-126), indicating the synthesis of ANP within the testis. This was supported by the detection of ANP messenger RNA transcripts (Northern blot hybridization) in the testis. These data indicate that ANP is expressed in the rat testis and support the notion that it may function in a paracrine and/or autocrine fashion in this organ.


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
W. Xia, D. D. Mruk, and C. Y. Cheng
C-type natriuretic peptide regulates blood-testis barrier dynamics in adult rat testes
PNAS, March 6, 2007; 104(10): 3841 - 3846.
[Abstract] [Full Text] [PDF]

Home page
 EndocrinologyHome page
D. Muller, A. K. Mukhopadhyay, R. C. Speth, G. Guidone, R. Potthast, L. R. Potter, and R. Middendorff
Spatiotemporal Regulation of the Two Atrial Natriuretic Peptide Receptors in Testis
Endocrinology, March 1, 2004; 145(3): 1392 - 1401.
[Abstract] [Full Text] [PDF]

Home page
 Biol. Reprod.Home page
F. El-Gehani, M. Tena-Sempere, H. Ruskoaho, and I. Huhtaniemi
Natriuretic Peptides Stimulate Steroidogenesis in the Fetal Rat Testis
Biol Reprod, August 1, 2001; 65(2): 595 - 600.
[Abstract] [Full Text] [PDF]

Home page
 Endocr. Rev.Home page
L. Gnessi, A. Fabbri, and G. Spera
Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment
Endocr. Rev., August 1, 1997; 18(4): 541 - 609.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
A. A. Kapasi, R. Kumar, J. R. Pauly, and K. N. Pandey
Differential Expression and Autoradiographic Localization of Atrial Natriuretic Peptide Receptor in Spontaneously Hypertensive and Normotensive Rat Testes: Diminution of Testosterone in Hypertension
Hypertension, November 1, 1996; 28(5): 847 - 853.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1990 by The American Society of Andrology.