| Condition (No. of Subjects) |
Outcome of Treatment
|
Placebo Control |
|
| Parameter(s) Improved |
Pregnancy, % |
Reference |
|
| Normogonadotropic infertility (14) |
Sperm count |
7 |
Yes |
R nnberg,
1980a |
| Oligozoospermia (93) |
Sperm count |
16 |
No |
Abel et al, 1982 |
| Oligozoospermia (29) |
Sperm count |
14 |
Yes |
Wang et al, 1983 |
| Oligozoospermia (11) |
None |
9 |
Yes |
Sokol et al, 1988 |
| Asthenozoospermia (70) |
None |
10 |
Yes |
European Metrodin HP, 1989 |
| Normal volunteers (79) |
None |
0 |
No |
Jungck et al, 1964 |
| Oligozoospermia (69) |
Sperm count |
5 |
No |
Palti, 1970 |
| Oligozoospermia (114) |
None |
19 |
Yes |
Foss et al, 1973 |
| Oligozoospermia (101) |
Sperm count |
19 |
No |
Schellen and Beek, 1974 |
| Oligozoospermia (32) |
Sperm count |
13 |
No |
Paulson et al, 1977 |
| Oligozoospermia (54) |
None |
4 |
No |
Charny, 1979 |
| Oligozoospermia (92) |
None |
17 |
No |
Newton et al, 1980 |
| Oligozoospermia (53) |
Sperm count |
14 |
No |
R ss et
al, 1980 |
| Oligoteratozoospermia (76) |
Sperm count |
10 |
No |
Rnnberg,
1980b |
| Oligozoospermia (101) |
Semen volume, sperm count, and sperm motility |
13 |
Yes |
Micic and Dotlic, 1985 |
| Normogonadotropic oligoteratoasthenozoospermia (89) |
Sperm count and density |
24 |
No |
Homonnai et al, 1988 |
| Oligozoospermia (89) |
None |
24 |
No |
Breznik and Borko, 1993 |
| Oligozoospermia (16) |
Sperm count and motility |
— |
No |
Epstein, 1977 |
| Oligozoospermia (NA) |
Sperm motility, morphology, and density |
— |
No |
Hayashi et al, 1988 |
|
| Abbreviation: European Metrodin HP, European Metrodin HP Study Group; NA, not
available. |
|