Figure 10. Sequence of the process of tyrosine phosphorylation of head membrane proteins (n = 6) and its relation to capacitation kinetics (n = 4). Open triangles represent changes in cell proportions in class P21, open squares represent changes in cell proportions in class P22, closed triangles represent the changes in CTC pattern of capacitated cells (B) closed squares represent the changes in CTC pattern of AR cells. All data fitted the linear function of time: P21 = 0.062t + 3.5, R² = 0.90; P22 = 0.028t - 0.3; R² = 0.74; B = 0.056t + 4.2, R² = 0.95; AR = 0.029t + 2.3, R² = 0.92. The kinetics of patterns P21 and B as well as P22 and AR (pairwise) are represented by similar mathematical functions with the close identical rate of changes as given by first derivatives: d(P21)/dt = 0.062; d(B)/dt = 0.056; d(P22)/dt = 0.028; d(AR)/dt = 0.029. The changes in these patterns progressed approximately at the same rate.